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HP0-M19 exam Dumps Source : HP Virtual User Generator Software

Test Code : HP0-M19
Test appellation : HP Virtual User Generator Software
Vendor appellation : HP
: 59 existent Questions

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What’s raw This HP Museum Stuff, in any case? | killexams.com existent Questions and Pass4sure dumps

Ken Kuhn (Fig. 1), an adjunct professor in the fork of Electrical and laptop Engineering at the tuition of Alabama at Birmingham, wrote Bob Pease again in January of 2006, “just a short notice to acquire you watchful about my net site devoted to analog electronics and background. acquire the vivid tour of my shop and museum (Fig. 2). This could breathe one of the most biggest domestic electronics stores any place. raw of this passe analog electronics is menu driven using analog GUI— the gadgets role the feature the knobs point to. No programming required. aid menus no longer essential. I regain pleasure from your column in digital Design— hold up the respectable work.”

1. Ken Kuhn along with his cat in entrance of a working bench at his HP Museum in Alabama. (Courtesy of Ken Kuhn)

2. As an analog aficionado, Kuhn’s cache of frigid witness at various gadget furthermore has Tektronix, accepted Radio, and lots of different historic, basic examine gadget. (Courtesy of Ken Kuhn)

Pease thanked Ken for the laud about his articles and added an emphatic “That, i admire!!” regarding the analog GUI (graphical user interface). After reviewing the web site, Pease noted,

“in one paragraph you say, "There ought to breathe a publication...." I noticed the booklet concerning the 25 very best items of HP; that got here out from HP, a brace of dozen years in the past. Or turned into it 18 or 20? I purchased and studied it and discovered some. conclude you fill that publication? I conclude not know where I do mine. It was once first rate mattress-time reading. conclude you fill got a "wanted checklist" of historic HP instruments or pilot Manuals? I, too, used to study the schematics of the novel gadgets reminiscent of Tektronix, HP, information Precision, and so on. and many others. at the moment, every thing is so computerized, and most of it, I hate. Menus, I hate. I opt for your analog gui. it breathe relish analog PowerPoint. hey, in a brace months, can i ship individuals to your museum? there's additionally a Philbrick Archive, and i should soundless furthermore send individuals to witness at that. finest regards. / rap”

Pease should fill pored over Ken’s website again, due to the fact four hours later he wrote lower back, “howdy, Ken. it really is a really excellent museum! firstly i was worried about those tall racks of machine (Fig. 3), were just an invite for an earthquake to knock raw of them down. however as you look to are living in Alabama, I guess they're secure. i hope you don't look to breathe too near to that earthquake site in novel Madrid, Illinois, or Missouri, or something. I guess you are at the least 100 miles away, permitting for the size of Mississippi. Very first-class work!!”

three. Bob Pease involved concerning the earthquake stability of those tall racks in Kuhn’s assortment. Kuhn assured Pease that there were few earthquakes in Alabama, and the racks are laced to posts conserving up the roof. (Courtesy of Ken Kuhn)

Kuhn wrote back,

“I are living in Birmingham, Alabama so earthquake random is minimal. despite the fact, the row of racks is going to breathe secured to the condominium posts (I referee they are obscured in the photo) just for coverage.

“As for the HP publication you mentioned. i am not watchful of that specific one. despite the fact, there changed into an HP publication that was posted in 1983 titled, ‘inventions of possibility: Matching know-how with Market needs.’ This publication became chosen articles from the HP Journal. This publication featured about 31 significant HP instruments. I even fill this book and it's astonishing reading. That may breathe the one you are speaking about. FYI: there are two books in regards to the heritage of HP that are being written now and that i pot could breathe published this year or next. One is a biography of Mr. Hewlett, Mr. Packard, and the enterprise, and is being written by passage of Michael Malone— a confidential writer of books about Silicon Valley. The other booklet is being written through two former HP employees and may breathe more in regards to the enterprise.

“As for a crave list for HP device, I conclude fill a minimal checklist, I personal most every thing else. This record contains an HP204A oscillator and manual. This one become a battery-operated vacuum tube moveable unit and is very infrequent. I actually fill the extra common HP204B, C, and D contraptions. additionally an HP200T oscillator. this is a unique version of the HP200 collection oscillators for telemetry testing. it is the most efficient 200 collection oscillator I shouldn't have. i conclude know there are just a few more, however my intellect is blank for the time being.

“i am attracted to finding an HP803A VHF Impedance bridge and the HP417A VHF detector that goes with it. I actually fill these in my collection, however HP is interested in acquiring this set for the archives. remaining drop i was contacted by means of craft Fong in Palo Alto (see some article links about him on my internet web site page about HP men and women) who turned into the engineer who developed these and he discovered them on my web web page. He changed into working with Anna Mancini (HP company archivist) attempting to locate these for a documentary HP changed into filming. I didn't want to sell my instruments however provided to mortgage them for the film however cut-off dates ran out. Anna told me that HP nevertheless desired to purchase a group. I talked about that i'd wait for some to demonstrate up. I even fill checked every source i conclude know but no success up to now— these contraptions are very rare.

“feel free to mention people to my net website. I furthermore can provide very own tours. One income adult from Agilent is planning to acquire the tour subsequent time he's on the town. plenty greater is coming for the net site as I fill time, so verify returned every so often to witness novel material. I loved assembly you about two years ago if you had been doing a country wide Analog Seminar in Huntsville. Hope to witness you again at some point. i'm well-known and widespread locally for my analog electronics talents. i was literally drafted a long time in the past to train night analog electronics on the university of Alabama, Birmingham. I actually fill been doing that for in regards to the remaining 18 years besides my day job. concerned with now, Ken.”

Pease instantly forwarded the thread to me and a few chums. He noted, “hi, guys, this memo includes his "need record". I bet, even here within the Valley, it might breathe slim pickings to find such ancient stuff. I instructed him he requisite to post a minute "wanted" region on his web pages. / rap”

I dropped a notice to Kuhn to inquire license to race his pictures and quote him. He introduced:

“I truly miss Bob Pease. He changed into my character of guy. I fill a brace of emails with him and furthermore bought to fulfill him some years in the past. i am now retired however am working pretty much complete time on an enchanting analog electronics mission i was drafted into. I fill an article in digital Design about corridor networks used to acquire notch and bandpass filters. there's additionally a pdf of the content on my very own web site. I even fill been contacted via just a few individuals who saw it and had enjoyable functions.

“I furthermore operate the HP recollection task, which become developed by a friend of mine, Marc Mislanghe, who worked for HP France. unfortunately, he died in 2014 and i was drafted to acquire over the web site. The web site is large with lots of data and memoirs of former HP engineers.

“some of the books that had not been published at the time of my correspondence with Pease is ‘The HP Phenomenon’ written through Charles house and Raymond price. It was posted in 2009 and i am outlined within the book. i conclude know Mr. house and provided a minute analysis for him. The Michael Malone e-book is ‘invoice and Dave.’ I met Mr. Malone and supplied him some research too. round 2007 I donated an HP417A and HP803A to the Agilent background core. I additionally donated an HP200B oscillator to Stanford institution and it is on screen on the HP storage reveal on the Huang Engineering center.

“I fill had the pleasure of an interior tour of the well-known HP garage and apartment. There are YouTube video clips [check out one of them below] of shows on the HP company auditorium that my friends, Glenn Robb, Marc Mislanghe, and i did again in 2007 about their HP historical past toil and websites. The Hewlett Packard Archive site operated by Glenn Robb furthermore has loads of HP information.”

I should additionally point out my buddy and fellow tech creator Steve Leibson’s web site concerning the HP 9825 computing device computing device from 1977. The web site has counsel on prior and later HP computers as neatly. Leibson writes with the conviction of a former Colorado HP employee.

Stanford professor Tom Lee advised me about HP giving a unreasonable school scholar an oscilloscope returned in the Nineteen Sixties. Kuhn knew raw about that legend and forwarded me a 2009 electronic mail titled “A heartwarming HP story.” It turned into by using Ken Chalfant, the engineer who received the free ‘scope. Chalfant wrote:

“My legend related to Hewlett Packard begins in 1967 when i was a junior unreasonable college student, age 13. i used to breathe already absolutely focused on electronics, owned an EICO VTVM (vacuum-tube voltmeter), and was trying to shop up cash to buy a package-kind oscilloscope from HeathKit. My science class went on a tour of the autochthonous HP plant perquisite here in Colorado Springs, CO. Wall to wall, as far as I might see, fill been oscilloscopes and test apparatus thus far past awesome that I practically had a seizure.

“when I acquired domestic I referred to as out to the plant and asked if they had any used scopes for sale. ‘We conclude not sell their used machine.’ got here the reply. ‘How a lot is your cost efficient scope in apparatus kind?’ I asked. ‘We do raw their machine collectively, they conclude not proffer kit kind.’ become the reply, adopted by using ‘Would you relish a catalog?’

“My mom took me out to the plant and i met Norm hall, the autochthonous advertising manager that I had talked to on the cellphone. He gave me a replica of their catalog. Oh my! What a catalog. It changed into very nearly an inch thick of shiny pages stitched hard-certain into a fine e-book. I took it raw over and wore it out. It became no longer most efficient complete of their gadget, but a very capable deal of tips on how their machine labored and how to succeed it. That catalog changed into my first electronics instrumentation text book. I soundless fill that accurate reproduction and that i fill additionally purchased a pristine copy for my library.

“i was not ready to give up on getting an HP scope, so I wrote Mr. Hewlett a epistle and asked him if I might buy a used one. neatly, to hold a protracted legend a minute shorter, Mr. Hewlett gave me a 120B scope. Forty years to the month later, Agilent [now Keysight] rediscovered the legend of what Mr. Hewlett had carried out for me. Jay Alexander, now CTO of Keysight, invited me out to the factory as a visitor speaker to contend Mr. Hewlett and the ‘ancient’ HP days, even though I even fill on no account worked for HP. Then they did it once again— they gave me one other scope (Fig. four), an MSO6054A. Wow, what an awesome oscilloscope. i really relish it!

4. As a 13-yr-old electronics lover, Ken Chalfant wrote bill Hewlett asking to purchase a used oscilloscope. Hewlett sent him a fresh one. Forty years later, Agilent (now Keysight) celebrated the event by means of giving Chalfant another free ‘scope. (Courtesy of Ken Chalfant)

“It’s grotesque that a man I in no passage met and a corporation I certainly not worked for fill had any such profound and nice influence on my existence. Mr. Hewlett and a few Colorado Springs engineers relish Blair Harrison, the heart beat generator lab supervisor who kindly tolerated me, giving me constituents, and turning me free to treat with his engineers at the plant, helped me so lots when i was simply a child. Then after telling ‘my’ legend and assisting them bear in intellect how surprising Mr. Hewlett and HP in reality had been, they ‘framed’ my life through giving me one more scope.

“Of direction, i am fully biased, but I doubt there will ever breathe two more gargantuan and honorable industry people then Mr. Hewlett and Mr. Packard. I don't feel anyone will ever construct a company with a view to acquire a contribution as a much deal in technical terms and so a capable deal extra in human terms than did Mr. Hewlett and Mr. Packard. Agilent [now Keysight too] nevertheless makes excellent apparatus and there are many outstanding, caring, involved americans working there, however without Dave and bill, Agilent is not, and under no circumstances might breathe the ancient Hewlett Packard.”

After checking with Chalfant for license to race his picture and words, he referred to, “I fill raw the time been a minute shocked, probably humbled is a stronger note, that I actually fill been blessed more than as soon as by using Mr. Hewlett’s variety generosity. In a diminutive manner the legend is ready me as a child, however in an even bigger passage the legend is raw about Mr. Hewlett. It in reality is an occasion to capitalize perception into one of the crucial two men who created the most efficient industry in an trouble to ever exist. by using comparison I don’t referee there are any much company leaders. growing to breathe up, my friends envied activities heroes, rock-n-roll stars, and movie stars. I didn’t suffuse about any of that. The one man I admired, and nevertheless do, is Mr. Hewlett.” Chalfant then brought, “I nevertheless have, and may at raw times have, that a hundred and twenty-B oscilloscope.”

Like Chalfant, i'm biased as smartly. I consulted to the HP automotive methods Division again in 1998. The HP approach changed into alive and smartly, and it turned into one of the vital greatest jobs I ever had, with the greatest boss I fill ever met. If any of the brand novel HP entities, Keysight, or Agilent, or HP commercial enterprise, are looking to breathe mindful the fierce loyalty they fill got from engineers, they should soundless believe about how invoice Hewlett and Dave Packard handled a juvenile junior high faculty kid from Colorado, and the passage they impressed college professors and others to document the business’s legacy (Fig. 5). it's the passage you build a company.

5. one more working bench in Ken Kuhn’s HP Museum. celebrate the music lighting fixtures for the benchtop. (Courtesy of Ken Kuhn)

That Colorado Springs advertising and marketing manager giving a 13-year-old child a pricey complicated-sure catalog did not aid that quarter’s revenue. Yet the lengthy-term improvement to HP/Agilent/Keysight/HP industry is just about incalculable. That’s the change between advertising and marketing and revenue. greater agencies should learn that.


5 methods Your company is susceptible to Cyber attacks | killexams.com existent Questions and Pass4sure dumps

Hackers understand a first-rate target when they spot one. lamentably, small-to-midsize companies (SMBs) are often these top objectives. a lot of diminutive company owners want to feel that malicious attackers don’t fill anything to capitalize via going after “the minute guy,” or that they don’t fill plenty to lose.

That’s with no cataclysm not the case. Sixty-one p.c of SMBs were hit by means of cyber attacks, and the touchstone can suffuse of these breaches has handed $1,000,000. listed here are one of the convenient ways in which hackers barge their manner into diminutive industry networks.

Malware

Malware is malicious utility designed to infiltrate computing device programs and extract any well-known guidance it could find. It comes in several different types, including viruses, adware, Trojans, rootkits, and worms.

devoid of the perquisite protection plans in location, malware can race rampant on instruments, amassing raw types of facts devoid of the user even realizing. and people insurance policy plans ought to breathe backed by using a security crew that understands the fast-paced world of malware – sadly, within the first quarter of 2017, a novel malware specimen emerged every 4.2 seconds.

Phishing

A phishing rip-off happens when cyber attackers send fraudulent emails pretending to breathe from a depended on source, but lead individuals to inadvertently deliver very own or professional suggestions straight to a hacker by the expend of a malicious site hyperlink.

a lot of people believe they’re too smart to regain caught up in a phishing scam. with the aid of now, as an example, most people know that a Nigerian prince doesn’t truly want to partake his fortune. however hackers are at raw times setting up centered, refined emails that look unquestionable and comfortable. for instance, protection consultants are at present worried about a phishing assail the station victims regain hold of an email that seems relish one despatched from FedEx. The email instructs the recipient to click on on a link that claims to serve them manage a package beginning, but in its place, clicking on the link offers a hacker access to their device’s device and suggestions.

Ransomware

just relish the identify implies, ransomware attackers exact a suffuse in an trouble to quit their attack, making this one of the crucial frustrating and devastating expertise breaches. during a ransomware assault, hackers unfold malicious software during a appliance or a complete equipment. The software shuts down those devices or techniques until a fee has been made. in addition to figuring out whether or not to fork over funds to the individuals attacking them, SMBs furthermore fill to spend cash bolstering their safety systems and making up for the lost productiveness.

a kind of most wide-accomplishing ransomware assaults became the WannaCry worm of 2017, which hit greater than 230,000 computers across the globe that fill been running out of date or prostrate systems. The attackers demanded $300 in bitcoin from their victims, threatening to delete critical information if the ransom wasn’t paid. Most didn’t pay the price, but they nonetheless had to wait days for security fixes to breathe issued. The assault crippled England’s country wide fitness equipment, shut down Australian speed cameras, forced a Honda factory in Japan to near down, and raw in raw is estimated to fill can suffuse victims within the billions.

Spoofing

Spoofing assaults occur when the hacker sends out emails pretending they’re a person they’re not. for example, attackers send out an email that appears to breathe from the company’s CEO or HR fork requesting data on private industry facts. An worker would then ship that data along to who they believe is their superior, but is really a cyber attacker.

In a case relish that, spoofing emails can distress a SMB directly. however they can additionally trigger devastation by passage of indirect techniques, as well. for example, German banking chain Deutsche monetary institution these days had to pay a $30 million first-class after two of their former merchants launched a a hit spoofing assail that manipulated the costs of valuable metals futures on the commodities market. A banking tremendous can afford that price, however diminutive companies could no longer breathe able to fill enough money the losses that could Come from believing fraudulent, incorrect advice about the markets.

Rootkit

Rootkit is sneaky and clandestine utility that enables an out of doors consumer to acquire control of a appliance devoid of the proprietor’s competencies. relish any other cyber assaults, that control offers a hacker entry to the equipment’s at ease community and files. however a rootkit is additional unhealthy as a result of, moreover getting access to these files, the hacker furthermore has complete manage of the equipment. That means they could alter community configurations, falsify files, override safety mechanisms, and infect the apparatus with extra malware. The attacker can furthermore undercover agent on the device’s owner, as an instance by using recording every sites they consult with and supplied credential tips. unfortunately, rootkits are very problematic to become watchful of and almost always require the toil of professionals to remove.

one of the crucial threatening rootkits is LoJax. security specialists fret that they've handiest seen the dawn of this rootkit, which is currently spreading. at the moment, attackers are using it to regulate protection programs and then infect gadgets with much more malware. since the attackers retain ply of the machine, they can breathe sure that the malicious application is done, raw with out detection. Researchers worry that attackers will expand even more sophisticated LoJax breaches within the months and years to Come back.

making unavoidable complete safety

So what can diminutive groups do? For starters: regain a VPN. VPN stands for virtual inner most network, and it’s a solution that many organizations expend to champion lower the occasion of a cyber attack. The network is encrypted and sometimes requires varied authentication methods, making it easier for remote laborers and employees in numerous branches to securely entry the purposes and programs they requisite to conclude their jobs.

It’s a much first layer of insurance plan. but with a purpose to breathe unavoidable total security, diminutive corporations requisite a safety plot in region so that you can protect that VPN in addition to acquire unavoidable that each device carries a brace of layers of coverage. HP provides exactly that. The industry knows that each pc resolution is a security resolution, and it equips every of your company’s gadgets with the apparatus they should cease vulnerabilities from each perspective.

classes relish HP bound start, HP sure regain better, and HP sure click on quit malicious utility from spreading to a company’s contraptions and network, managing raw competencies threats so a diminutive enterprise can seat of attention on edifice its enterprise. within the case of an assail relish LoJax, HP unavoidable birth would breathe in a position to live one step ahead of the game with the aid of detecting the assail before it might acquire place. LoJax gets in with the aid of attaching itself to the BIOS, which is the primary million strains of code that a appliance runs before being turned on. HP unavoidable delivery recognizes rootkits relish LoJax at the BIOS stage, and then fully replaces the BIOS to ensure that LoJax doesn’t fill a ride into the system.

The danger is real, but hope isn’t misplaced. With the commandeer figuring out of their personal vulnerabilities and an HP cyber safety plot in location, diminutive company owners could acquire commercial enterprise-level protection decisions if you want to flip them from a hacker’s best goal to a hacker’s useless conclusion.

be trained extra at hp.com

Futurism enthusiasts: To create this content, a non-editorial team labored with HP, who sponsored this post. They aid us hold the lights on. This post doesn't always replicate the views or the endorsement of the Futurism.com editorial cadaver of workers.


assist! My Isolator Is Taking Too lengthy To Degas — What may soundless I Do? | killexams.com existent Questions and Pass4sure dumps

by passage of Herman Bozenhardt and Erich Bozenhardt

likely probably the most huge developments in sterilization and aseptic practices in the pharmaceutical enterprise is that of vaporized hydrogen peroxide (VHP) as a contact or “cold” sterilizing agent. the expend of VHP in contained environments has allowed us to decontaminate working areas, machine, and substances and has resulted in the progress of the respectable isolator. This application has ended in many years of success and supplied assurance that aseptic dealing with and filling operations are microbial-free. in this article they will focal point on filling isolator programs and equipment. considering the expend of this expertise started, they fill been singularly concentrated on sterility with the aid of maximizing injection quotes and saturation stages and assuring media fills are a hit in qualification checking out.

a different evolution of this know-how is the size, complexity, and variety of isolators the VHP has been applied to. at the start isolators fill been “bins” or “cylinders” with lots of injection nozzles and an easy HEPA exhaust scheme. these days the isolators fill increased in measurement so much that the height and width require extra nozzles and more advantageous attain throughout the fill deck. additionally, we've isolators with seven to 13 sections, with distinctive reform angles to adjoining sections where each and every region can furthermore breathe 10 to 20 meters lengthy, and with several auxiliary docking sections. In raw these circumstances they compensate with extra VHP injection as a result of they deserve to acquire sure a hit media fills.

New truth

As this enlargement of VHP expend and isolator complexity evolves, we've driven ourselves directly into the newest classification of drug items and fill “hit the wall.” they fill discovered many novel therapies which are labeled as “ultra-low” potency items (in the microgram and nanogram per ml), biologicals that are sensitive to VHP (and any oxidizer within the vapor phase) and incompatible items (in some instances there become no prior checking out or consideration for VHP interaction). In these instances, the residual VHP vapor within the isolator interacts with the open vial of liquid between the dosing nozzles and the capping station and oxidizes the API in the solution. This turns into a more severe problem with lyophilized items, the station the liquid is uncovered from the dosing needle in the course of the fluted stopper and into the lyophilizer itself. This has had an well-known fill an repercussion on on novel installations and CMOs as they acquire novel enterprise of their legacy aseptic filling isolators. In some circumstances, the residual VHP has attenuated product by 10 to 15 % efficiency in middling fills and up to 25 p.c degradation in lyophilized creation.

For the CMO, this frequently violates lots of their habitual practices and crushes their high self assurance in their VHP cycle and media fill, and that they must physiognomy the truth of many isolator alterations and doubtlessly decreasing their VHP cycles. This additionally exposes a flaw: that some isolator VHP residual levels fill in no passage been understood, challenged, or questioned. in lots of situations with low-efficiency items or biologicals, they deserve to set the residual degree from the one hundred +/- ppm tiers to as low as 10 ppb. Some may inquire yourself if this conceivable, and the reply is absolutely. although, some practices, gadget, and strategies requisite to trade, and for the stronger. they will now ascertain the system of degassing and doing away with residual VHP by passage of aeration from the a variety of industry isolators.

incorrect “options”

As we've dealt with these issues on a global degree, they now fill discovered individuals who referee outside the container and strategy the problem with greater complications:

  • “Let’s simply fill with a much better awareness.” This system of concentrating the product and letting the degradation acquire its toll is foolish. that might require a change to the submission files and exhibit a requisite of examine of the compatibility of VHP with the product. furthermore, the oxidation of the API produces a compound, and now they would fill introduced a novel impurity. The FDA could breathe very attracted to this.
  • “Let’s raise the fill extent.” here is equally inappropriate, as the equal issues as above will occur, with a degraded efficiency and more quantity. The residual generated should breathe wondered, as will the manufacturing submission.
  • “Let’s just HEPA-ventilate until they regain a very capable reading.” while here is a compliant solution, it outcomes in a degassing that may acquire days or even weeks to accomplish. This may fill a devastating fill an repercussion on on product birth and plant means. by using unreasonable sparkling air ventilation, they are furthermore stretching the service life of the internal HEPA filters while increasing the operating can suffuse geometrically. The air coping with unit (AHU) and cooling charges will drive up the vitality load.
  • “Let’s observe if they are able to Cut back on the validated VHP cycle and notice what happens.” this is a risky approach, for the intuition that any exchange to the procedure would require a metamorphosis control and re-execution of media fills. without any engineering alterations, this is a pot at choicest.
  • The most profitable solution

  • Recognizing VHP and its residual exist and could fill an repercussion on the product is the first step in averting a problem. it is crucial to acquire expend of the product and race VHP compatibility checks, challenges, and fill trials to collect facts and bear in intellect the repercussion earlier than the fill is tech-transferred into the isolator web site/atmosphere. This should breathe performed in a pilot plant or, at worst, in a “development” mode with the isolator. this may enable statistics to breathe gathered, a judgement reached on fill an outcome on, and a rational design accomplished earlier than the fill tech-switch. this may give parameters for the residual ppm or ppb of the VHP, the degassing time, and any container-based modifications crucial (alternatives below). The watchful design of the cycles (each VHP and degassing/aeration) and figuring out the VHP stages, temperatures, relative humidity, speed of aeration, air exchange fee (ACR) in the isolator, and ingredient HP values by means of instrumentation is helpful. A virtual 3D model of the residual VHP frequently enables pinpointing the well-known thing VHP supply. This proactive system saves time and funds and allows for for the selection of a superior economic answer, which is a tradeoff of engineering technologies and degassing time.
  • container-primarily based options

  • one of the crucial regular and omitted problems is liquid pooling in unavoidable areas above and below the fill deck. although, you're going to under no circumstances observe this at the short manufacturing unit acceptance verify  (fat), however after a brace of in residence VHP runs a gasket, opening, port, or other aspect allows for moisture collection and it will hold dissolved HP. A watchful study of the unit perquisite through and at once after the VHP routine (of the machine, the deck, and below the deck) is usually step one in troubleshooting.
  • The next key region to witness for is the elimination of polymer-based materials inner the isolator, certainly raw platinum-cured silicon tubing. raw polymer-primarily based cloth absorbs VHP throughout the cycle and slowly expresses it, however at a rate which will proceed to thwart the degassing. Some polymers are tremendously worse than others. The focus is to maximise stainless steel and expend Teflon, polyethylene, and polypropylene best when required. probably the most detrimental and absorptive polymers are Delrin, polyurethanes, polyamides, polysulfones, and polystyrenes. You fill to loom cautiously on the substances of edifice of your tubing, filters, seals, gaskets, and other polymer-primarily based add-ons. This additionally comprises the HEPA filters and mounting techniques. The person must bethink the substances within the HEPA filter frames above all. In some CMOs, the isolators fill HEPA filters on the return ducts/plenums. here's to prevent pass-infection; these filters (polymers) can furthermore breathe eliminated if the product profile does not hold cytotoxics, robust compounds, or energetic biologics.
  • together with the polymer-based investigation should soundless breathe a cautious evaluate of the gloves, glove ports, and different interface seals. First verify for materials of building, and then breathe sure the gloves are raw prolonged (fingers don't look to breathe collectively) and don't fill any obscured surfaces or cowl a port of one other polymer seal. Polymer surfaces trapped in opposition t one a further can additionally trap and retain VHP and intervene with touchstone aeration/degassing.
  • The isolators fill AHUs that ply the air circulating from the isolator deck-degree returns. These AHUs fill cooling coils to manage the temperature in the isolator section, which is essentially a cooling characteristic. The coils are fed chilled plant water internally to frigid the air drawn by passage of the blowers, which pushes the air through the HEPAs returned to the isolator for downward coverage of the vials. due to the fact that the AHUs are an immense working-charge contributor, they fill been optimized for suffuse reductions and minimum circulation and never for degassing. Rethinking design and orientation are essential to provider modern product strains.
  • The coils are cold during habitual operations and stay so raw through the VHP cycle (despite the fact that the chilled water give valve is shut). The coils are an awesome station for water to condense, bring together, and preserve HP (dissolved hydrogen peroxide). once pooled during this area, it may acquire days to evaporate the water and the HP. here's one of the most typical vicissitude areas.

    to ensure that this region not to pool liquid and revolve into the HP reservoir for the unit, the ply apparatus requisite to condition the isolator coils for a do up-batch/pre-VHP cycle. In some designs, there isn't any temperature manage unit (TCU) for heating and the valves control the chilled water going perquisite into a recycle mode and slowly let the heat from the isolator and machinery warm the air movement. In a extra modern design (see AHU scheme), a TCU provides either plant scorching water or electrically heated water to bring up the temperature of the coils and the internals of the isolator.

    during this case, throughout the middling isolator-filling scheme the programmable common sense controller (PLC) controlling the isolator AHU has a calming water (CW) set aspect CT that has valve VB controlling the chilled water circulating (valves VA and VD are closed, and VC is open 100%). To prepare for the VHP cycle, the PLC needs to expand the temperature of the coils above the condensing temperature of the VHP (be watchful the coils and blower are upstream of the HEPA filters). This temperature should breathe 35 levels Celsius and will breathe attained rapidly. this can require a TCU to return online with its pump, shut VB and VC and open VD 100 percent, and control the temperature by passage of actuating valve VA and inserting the TCU mode to warmth.

    The subsequent step is to race the isolator VHP cycle, realizing the coils are heated. once the VHP cycle is completed, the degassing may soundless reinitiate the coil-heating cycle and compel the temperature of the entire isolator up and speed up the degassing, making bound any residual VHP and water/HP evaporates quickly.

    As in raw of these styles of applications, an in depth time-based analysis of the PLC cycle is crucial, as an inadvertent activation of a chilled water line, a incorrect set point for a short duration of time, or a valve sequenced incorrectly may well breathe the root explanation for the AHU issues.

  • probably the most worthwhile investments in an isolator is the VHP/HP absorbing leavening that may furthermore breathe do in within the AHU. These leavening techniques are ultimate to instantly soak up the VHP from the isolator throughout their recirculation mode. the well-known thing to effectivity of the isolator is its means to recirculate air and best bleed in “make-up” air. The leavening must breathe placed by means of leavening specialists in coordination with the isolator company for the reform vicinity, air speed checks, PLC sequence of when to interact the catalyst, and common commissioning of the unit. This permits the isolator to race in its most advantageous (re-circulation) mode and absorb/wreck VHP. here is top of the line if it is completed within the design of device. If here's completed as a retrofit, the isolator can breathe taken out of service and may breathe re-commissioned, and re-execution of the media fills would breathe required.
  • Fan circulation of spotless air and recirculated air is an extra consideration. As mentioned above, the isolator usually runs in the mode of recirculation and decreased vitality consumption. The blowers are frequently variable frequency drives (VFDs), and the PLC controlling them may not breathe programmed effectively for optimum exhaust. The blower-controlling a allotment of the PLC must insure the lovers are in sync, no longer inhibited via the vigour administration scheme, and capable of generate an exhaust profile that flushes the entire isolator part. it is essential to understand the fluid dynamics in the isolator, no longer best throughout the VHP cycle, however the degassing cycle as well. These are diverse cycles with distinctive goals, and while dwell time and distribution are key for the VHP injection and downward speed of .36 to .forty five m/s are key for filling, they conclude not necessarily toil for the degassing/rapid air egress. The most efficient approach to assure ourselves the isolator is being degassed, now not leaving “useless zones” or growing vortices that recirculate the air or another anomaly, is to achieve a computational fluid dynamic (CFD) mannequin of the isolator. they fill too many cases where insufficient air turnover and useless zones are led to via gadget place, filling deck peak, fan region, and areas not evacuated cleanly. this can furthermore breathe existent of the many “docking station” options. in the end, your realizing of the air velocities, aeration profile, and delta drive throughout constrictions is vital.
  • An alternative that is awfully valuable, and additionally expensive, is the retrofitting of the filling system with a nitrogen “blow” into the vials, nitrogen backfill at dispense, and nitrogen blanket up to the stoppering zone. This does not expand the degassing; despite the fact, it protects the product as much as a stage. If carried out at the isolator design, the incremental cost is smartly contained. despite the fact, if executed as a retrofit, it may can suffuse a number of million dollars and detain operational expend by a year. a further consideration is that counting on a nitrogen headspace to protect the product will fill an repercussion on the regulatory submitting, as a novel ingredient has been introduced.
  • In summary, troubleshooting of a degassing/aeration issue of an isolator requires quite a lot of time, evaluation, and persistence. To Cut back a VHP stage in an isolator from 50 ppm to 50 ppb may acquire months. that's why nitrogen backfilling plus isolator CFD analysis, polymer elimination, and cautious temperature ply can insinuate the change in over a year of startup time and better competence throughput.

    about the Authors:

    Herman Bozenhardt has 42 years of event in pharmaceutical, biotechnology, and clinical machine manufacturing, engineering, and compliance. he is a recognized knowledgeable in aseptic filling amenities and techniques and has extensive event within the manufacture of therapeutic biologicals and vaccines. His latest consulting toil makes a speciality of the areas of aseptic programs, biological manufacturing, and automation/computer systems. He has a B.S. in chemical engineering and an M.S. in gadget engineering, each from the Polytechnic Institute of Brooklyn. that you would breathe able to compass him at hermanbozenhardt@gmail.com or unite with him on LinkedIn.

    Erich Bozenhardt is the technique supervisor for integrated chore features’ procedure neighborhood in Raleigh, NC. He has 12 years of experience within the biotechnology and aseptic processing industry and has led a few biological manufacturing tasks, together with mobilephone cures, mammalian phone lifestyle, and novel delivery methods. He has a B.S. in chemical engineering and an MBA, both from the school of Delaware. that you can attain him at ebozenhardt@ipsdb.com or connect with him on LinkedIn.

    Isolator image courtesy of ProSys


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    Welcome back. In allotment 1, they covered a common framework for how to acquire sense of paradigm shifts in the world. This section, although it covers its own topic, can breathe read as a continuation of allotment 3 (Our shift from a driver-centric to a car-centric culture).

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    Around the revolve of the 20th century, they developed a novel capability: to transform that energy into electric current which could flood through wires. This unlocked a very well-known novel possibility: to consume energy elsewhere from the power source. Then they took a step further: they organized those wires into an electrical grid, enabling many different power plants to serve a distributed group of customers. Consumers gained a second freedom — to expend energy at the time of their choosing, as any one customer was no longer matter on a specific plant being online at any given moment. These two novel powers — freedom of station and liberty of time to consume electricity, so long as you were plugged into the grid — dramatically increased what could breathe done with a joule of energy. silly enough, they don’t actually fill a succinct sole word to record this combined effect: the competence to consume a joule of energy at the time and station of your choosing. So I’m going to abbreviate that concept as “dxdt” for this argument, which you can referee of as a sole quantity representing “place-shift-time-shift”.

    The following point is well-known to understand: from any user’s point of view, you can’t really separate the dx (place) and the dt (time) components of dxdt. So long as you are connected to the grid, it does not matter where or when you revolve on your light switch: it will disappear on. This is why you sometimes hear people well versed in energy bellow “The grid is a battery.” It’s not literally a battery- but to any observer, it acts relish one. For anyone putting energy into the grid, you don’t fill to worry about who’s consuming it when or where; for anyone pulling energy out of the grid, you don’t fill to worry about who produced it, when or where. The lights disappear on, and that’s that.

    How is this the case? Because grid operators conclude a lot of hard toil to acquire sure the system is always in balance. The grid is relish a bathtub, always filled exactly to the brim, no more no less. Pulling off this balancing act is no diminutive task: it requires constantly monitoring your load, maintaining transmission lines, bringing novel plants off and online, and keeping extra capacity in reserve. This is raw expensive — about 50 cents on every dollar of their electricity bill disappear collectively to these various dxdt functions. But they pay this money for a capable reason: were there no dxdt, we’d breathe brought back a century: each of their homes would fill to breathe directly hooked up to a local power source, and their competence to revolve on the lights would breathe matter to that plant being online here and now. Hence, dxdt is a very valuable thing.

    All together, dxdt accounts for more than half of their energy bill. (PJM / Pennsylvania, 2013–2014)

    This brings us to their next well-known point: the grandiose compress of energy in the 20th century. As we’ve said before, the grandiose bargains limn those much compromises between scarce resources, around which an industry sits at equilibrium. In energy, what has it been for the ultimate hundred years?

    The compress has been this: in exchange for affordable dxdt, they accept a requisite of option for how they regain their energy. If you’re in San Francisco you only fill one option of electricity provider: Pacific Gas & Electric. The public utility commission grants them a sanctioned monopoly, in exchange for having a cap placed on what they’re allowed to suffuse you as a utility for providing you with dxdt. From time to time, PG&E goes to the public utility commission with a proposal for consumer electrical rates, who then approves those rates based on current wholesale prices of energy and other factors. In some deregulated regions, consumers can select among multiple providers of electricity, at least offering some choice, but upon making their selection soundless pay monotonously through a meter for a stream of commodity electrons. In essence, the regulated component of the rate they pay is not actually for the electricity itself (wholesale power prices are market rate and highly competitive) but rather for the dxdt component.

    This compress turned out to breathe highly productive. It do the perquisite incentives in station to electrify their cities and towns, to build high-capacity, trustworthy mainframe plants and to acquire sure that the lights always turned on, cheaply. But what now? As the 21st century opens, we’re presented to a world of novel possibilities but furthermore exigent resource and climate related problems to address. Technology will certainly serve determine what happens.

    How can they acquire sense of what’s going on? Let’s revolve to their concept of technology increasing access to scarce resources. With dxdt and option as the scarce resources of the 20th century energy bargain, they can categorize energy technology breakthroughs in terms of access to these two entities.

    In one corner, they fill novel technologies that expand their access to option of which joule of energy they consume. Renewable energy relish solar gives you one kind of choice: if the sun is shining, a solar panel owner can regain momentary access to zero-emissions, zero-marginal cost energy. very for wind. Consumer-sited energy is another: if you fill a generator of some kind on-site, even a simple 3 hp Honda gas generator, you can pick to expend that energy at your discretion. Rooftop PV systems and flaming water heaters are other examples. Smart appliances and systems that can revolve on and off intelligently in order to select the cheapest and best watts fill arrived as well. And at a far more granular level, the imminent arrival of distributed IoT systems will empower formerly static components to become actors that acquire choices of their own — we’ll Come back to this later. The repercussion of raw of this technology points in the very direction — away from the passe grandiose compress where you only had one option (the even grid) towards a world where a consumer might fill multiple options for how you source and consume your energy.

    Our collective response? We’re very excited about this increased access to choice, and we’ve heard a lot about how they requisite to build a “Smart Grid” to acquire handicap of these novel options. There’s just one problem: it’s proved quite challenging to regain anyone to agree on how this should toil and who should pay for it. In the meantime, increased access to option without improving their competence to shift energy in station and time (dxdt) leads to a lot of fights between stakeholders. What happens when the sun is shining but no one needs the energy? What about the opposite? Is Net Metering fair? If the traditional grid is the only network connecting the these distributed ‘choosers’, who is in control? Without a corresponding expand in dxdt, increased access to option leads to contest and no limpid industry model.

    Meanwhile in the other corner, there’s another category of technology that’s increasing access to dxdt: energy storage and electric vehicles.

    Energy storage is very clearly a contour of dxdt. It lets you draw in energy at one time and consume it at another (and possibly a different station as well). If there is high supply or exact for energy at time A and low supply or exact at time B, energy storage lets you bridge that gap and resolve the difference. Electric cars disappear a step further: they quite literally are a battery on wheels that can suffuse up at at different locations, expend that energy gradually as it drives, and even discharge its energy should the situation convoke for it. (Gasoline, which powers most vehicles on the road today, is furthermore a highly efficient contour of dxdt. It’s dense, portable, and standardized.)

    It’s worth repeating this point, because it’ll breathe well-known later: electric vehicles are a contour of dxdt, just relish the grid. One vehicle may not breathe able to store, ride or consume very much energy — but a gross fleet of them develop a capacity and an agenda of their own.

    In the meantime, a lot of people fill gotten excited about energy storage — specifically, the prospect of arbitraging energy from the grid, buying at off-peak hours and selling at peak prices to acquire money. This sounds relish a capable gig, but it actually isn’t: the economics don’t toil out. How come? Because without choice — without having many options from which they can regain energy — it’s very hard to acquire money in arbitrage. They can pick to buy power from the grid at 3 am vs. 3 pm, but that’s pretty much it. Without a corresponding expand in option of where their energy comes from, increased dxdt is mostly underwhelming and yields no clearly profitable industry model.

    But what about when they acquire a step back and observe that both of these transformations are happening at the very time?

    No one really knows what’s going to happen. But I conclude believe they can bellow the following:

    -The grandiose energy compress in the 20th century is predicated on dxdt and option as scarce resources around which the market is organized.

    -Increasing access to option of where, when and how they regain their energy makes dxdt more necessary and valuable.

    -Increasing access to dxdt, conversely, makes having access to different choices of energy at different times and places more valuable.

    -Consumer sited energy, renewables, smart consumption, batteries, EVs and other kinds of technology are currently increasing access to both option and dxdt, at the very time.

    We are very near to a minute not unlike when early PCs and the early Internet, which initially evolved separately, finally create each other.

    This should fill two consequences in the near-ish future:

  • A virtuous cycle, not unlike Moore’s Law, whereby more option enables more dxdt and vice versa in a self-reinforcing loop.
  • Dxdt and energy option will no longer breathe the central scarce resources of energy. Something novel will acquire their place. Much as the grid turned power plants into fungible abstractions 100 years ago, so will occur to the existing grid in the next few decades.
  • What might this actually witness relish in existent life? The combined Tesla + Solar City, or at least the concept behind the merger in principle, can serve us out as a conceptual starting point. Solar City is a company that increases access to option through their distributed, consumer-sited network of rooftop PV panels. Tesla, on the other hand, increases access to dxdt by deploying large numbers of electric vehicles, charging stations and Power Walls. I’m not adage Tesla + Solar City will surely emerge as winners, although we’ll revist them later. What I import here is the concept of Solar + EVs and its potential can best breathe understood as radically increased access to option and dxdt, in tandem — and that’s what makes it exciting. When they talk about Tesla / Solar City operating an “energy network” between its solar rooftops, cars and charging stations, this is what we’re talking about.

    Back to current reality — if access to option is increasing, and access to dxdt is increasing, what does that mean? What will breathe scarce?

    Here’s my best guess.

    The physical electrical grid as they understand it will soundless exist, and will continue to breathe operated by the public utilities we’re confidential with. Most of their energy will soundless Come from large, centralized sources — much of that from utility-scale natural gas, and eventually wind and solar. (Just as much of their computing today is soundless done in centralized locations. Mainframes persisted for a long time, and fill since been superseded by giant server farms powering the cloud). There’s nothing “off-grid” about this — the plants and wires they know today will soundless very much exist. Surrounding this centralized backbone of energy production and transmission they will furthermore fill a highly distributed network of small-scale production, storage and transmission. This network will fill many components: rooftop solar panels, batteries that can suffuse and discharge, electric vehicles, and their charging networks.

    You can referee of the relationship between the central trunk and the distributed peripheral branches as by far akin to that between Uber and a subway system. The subway system has a much greater absolute capacity along its trunk lines, and can ride a very high volume very efficiently within those parameters. Surrounding this trunk, they fill Uber — a highly diffuse, locally efficient passage to bring their electron passengers to and from the central lines, absorbing capacity variation, and even directly competing in situations where the economics permit. The majority of electrons will soundless acquire the subway for the majority of their journeys — but whoever can fulfill the many different kinds of “last miles” will probably fill the more attractive income proposition.

    The most significant change will breathe that this distributed network will effectively straddle and ultimately supersede the Meter: the literal counter that calculates their energy payments, and furthermore the dividing line between the two environments they currently convoke “In front of the meter” (utility-sited) and “Behind the meter” (consumer-sited). With the soar of consumer-cited generation and storage, particularly of the dispatchable kind (where utilities today can deploy and depend on these assets as if they were “Virtual power plants”), the line between what is in front versus behind the meter is poised to become very blurry- and ultimately disappear. So what replaces it?

    The meter most likely gets replaced by an entirely novel layer of energy where electricity can breathe stored, exchanged, and consumed. Almost relish a distributed “Internet of energy” that is not controlled by any master coordinator but rather operates relish a distributed commodity market. What will they find on this market? We’ll breathe dealing in one very basic commodity: electrons. But there will breathe a number of different ways that they might breathe handled. They will probably observe the creation of a few simple derivative contracts that supersede the monolithic counting of the meter and pay out based on some practicable underliers:

    -The productivity of an energy-producing entity, such a solar panel, gas plant or nuclear plant

    -The money paid out by an energy-consuming entity, such as a edifice or a car

    -The money earned through arbitrage by an energy-storing entity, such as a battery or a car.

    This commodity market character layer is fundamentally made possible, and in fact inevitable, by the distributed Internet of Things. Once these underliers become agents of their own (as they will), two very natural scarce resources should emerge: information and trust. Just as the grandiose energy compress of the 20th century stated, “In exchange for access to dxdt, you agree to restricted choice”, the grandiose energy compress of the 21st century may state, “In order to participate in this ecosystem, you must demonstrate and commit to the required even of trust.”

    What does “the required even of trust” mean? Well, there are many different ways to participate in this market, each with their own requirements. If you’re a homeowner and raw you want is for your lights to revolve on — in other words, for the market to act relish the electric meter we’re used to — then you requisite to provide a billing address, and maybe a credit history. If you’re a dynamic circuit breaker that needs access to the information held by an adjacent load balancer, you requisite to demonstrate the commandeer digital credential to breathe granted read or write permission. If you as an entity want to trade on this market, and expend information that you fill to try to acquire money, then that requires some higher even of trust. If you want to breathe a major player on the market — say, operate a fleet of electric vehicles that are constantly buying, storing, selling and consuming energy — that too requires many different and ongoing exchanges of information and trust. In time, some kind of regulation or self-policing will emerge, although it’s hard to bellow what at this point.

    Funny enough, if this comes to pass it will limn the final arrival of something they dreamed about in the 90s; one man in particular. That man was Jeff Skilling, and his dream was Enron. To breathe clear, let the record rightfully situation that Enron deserves its final resting station in infamy. But nonetheless, you can’t serve but referee that Skilling was clearly ahead of his time. But the the lesson from history is clear: for this to actually work, it needs to breathe a distributed system relish the Internet, and not a centralized model relish Enron’s. I don’t referee I requisite to elaborate why.

    So how does this actually Come about? As exemplar an endpoint as it may seem, this seems relish a pretty major change from the passage things toil today. Where are the most efficient wedges going to Come from? Who will hold the information? And who will hold the trust?

    Well, let’s disappear back to allotment 3, where they talked about cars and other technological changes that expand access. Specifically, they talked about their ongoing shift from driver culture to car culture, the increased access to cars and drivers brought upon by the mobile phone (Uber), and the coming increased access to liquidity brought upon by autonomous vehicles and fleet programs. They asked the question, “What will cars want?” But they held off from commenting about the third major wave of change coming to vehicles — their electrification — because they were saving it for this post.

    As it turns out, electric vehicles are going to breathe the perfect wedge into their novel energy paradigm for the following reasons:

  • They are a contour of distributed dxdt, as we’ve discussed.
  • The cost of producing and operating an electric vehicle (or a fleet of them) is heavily subsidized by its other function: transport.
  • They are going to breathe productive entities that can want things — and will probably regain them.
  • They will breathe significant energy consumers themselves, granting them leverage as dxdt entities.
  • And so, they now finally fill the perquisite lens to witness at what Elon Musk is planning for Tesla.

    We already heard about Tesla underhand Master plot allotment 1: expend momentum from the Roadster to build the Model S, and then in revolve the Model 3. Then they heard about Master plot allotment 2, which was largely about Tesla becoming a fleet manager of sorts (albeit with a bridge age where individual owners soundless own the cars). What’s going on in parallel, though, is quite a bit bigger in scope: expend cars as momentum to build Gigafactory production capacity and charging stations, and in revolve own the charging touchstone and therefore dxdt. In the future, GM, Toyota or Apple could acquire the cars; Musk and Straubel mostly suffuse about having them raw fill a Tesla-produced battery made in a Tesla Gigafactory running Tesla software and — most importantly — operate on the Tesla Charging Standard. That’s a existent business.

    Remember back when they asserted that the logical future scarce resources in the novel layer of energy were Information and Trust? If Musk can seize the charging touchstone for EVs, he has profound hooks into both of these resources. He can expend them as a powerful wedge into creating and owning the valuable parts of the novel energy commodity market — where Solar City makes lovely sense as an integrated product offering, I must add. That’s why, just relish in Chapter 3 where they mentioned about how one of the existent battles beneath the surface for Uber was for maps, the existent battle here for Tesla isn’t just for the cars. It’s furthermore for the charging standard, the stations, and for profound hooks into the underlying actors in the Internet of Things that participate in the novel distributed energy marketplace. Tesla doesn’t want to quit up as the Compaq of this transition — they’d much rather breathe the Intel (battery architecture), the Microsoft (driving / on exact productivity network), or the Cisco (charging standard). Or even more than one.

    One final point before they go. When they hear people talk about “The Smart Grid”, the massive and broadly supported Public-Private initiative to coordinate raw of this distributed activity, what is that going to be? I’ll regain in cataclysm for adage this, but when you hear “Smart Grid”, referee Sun Microsystems. Hearing “Electric cars, solar rooftops, and dynamic pricing will raw race on the Smart Grid” sounds an impoverished lot relish the passe tagline, “The Internet runs on Sun Microsystems.” Here’s the thing: that’s not wrong. The backbone and interconnecting glue of the Internet did race overwhelmingly on Sun’s SPARC architecture. (And soundless does, in a few places.) Sun was instrumental in making the Internet work. But in the long run, they did not win: they were caught between paradigms, not quite the passe and not quite the new. If a mammoth, centralized Smart Grid is their Sun Microsystems, then the distributed energy layer I believe will emerge might initially witness relish Red Hat Linux. For anyone looking for the next layer, that’s where I’d start my search.

    In summary, raw I can bellow is this: it’s going to breathe wild. We’re very near to their “PC, meet the Internet” minute for energy. When PCs came online, the world changed forever — and so it may breathe with their next layer of distributed energy. So many things are coming together: cheap renewable energy driven by the falling costs of solar and wind, an onset of highly subsidized energy storage inside of cars, the changing nature of the ownership of cars itself, and the emerging IoT glue that’s going to bind it raw together. No one knows what’s going to happen. And they can’t wait.

    Thanks for reading. If you’ve enjoyed this series, gratify partake with anyone who might breathe interested. We’d furthermore relish if you subscribed to Snippets, their weekly newsletter from sociable Capital (curated by me) featuring their current observations, links to what we’re reading, and advice from the much companies they toil with.



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